DR. PRIYA LAKSHMI KHANGEMBAM

DR. SHIBASHIS DEB, DR.ATHILI LESHINI, DR. SURABHI PRASAD

Abstract

Background: Myasthenia gravis (MG) is an autoimmune disease caused by autoantibodies against the acetylcholine receptor (AChR) at the neuromuscular junction. When the clinical manifestations of MG are limited to the levator palpebrae superioris, orbicularis oculi, and extraocular muscles affecting eye movement, it is referred to as ocular MG (OMG).

Methods: A 43 yrs old male patient presented to us with chief complaints of double vision in left eye and drooping of left upper eye since 20 days. On examination we found that ptosis increases more in the evening and after fatiguability test. Patient had positive Acetyl choline receptor antibodies . Tab.Pyridostigmine 30mg in QID dose was started.

Results: Patient showed significant improvement of ocular motor dysfunction on treatment with pyridostigmine.

Conclusion: The treatment is chiefly medical and aims at improving muscle weakness, achieving disease remission and slowing or preventing progression to generalised MG.