DR. ROLIKA BANSAL

DR. FAIROOZ PUTHIYAPURAYIL MANJANDAVIDA, Dr. KAUSTUBH MULAY, Dr.SANTOSH G. HONAVAR

Abstract

Purpose:To assess nature of medulloepithelioma(ME) of the ciliary body(CB), surgical intervention & possible conservative management.

Methods:Retrospective, interventional case series.

Results:19 patients had a median age 24(range, 1-792)m. Basal diameter 8.5±5.2(range 4–16)mm, thickness 4.7±2.9(1-8)mm with leukocoria12(63%), iris neovascularization10(53%), secondary glaucoma8(42%), vascularized retrolental membrane 5(26%), anterior chamber mass 4(21%), & lens subluxation 3(16%). Primary enucleation was in 10(53%) & adjuvant radiotherapy 2(10%).Histopathology 3(16%) were teratoid & 8(42%)malignant. Clock hrs <6 given chemotherapy in 7(37%), primary plaque brachytherapy in 1(5%), observation 1(5%) led to eye salvage in all. At follow-up of 102.8±82.3(range13–324)m, no local tumor recurrence/systemic metastasis. Conclusions:Timely diagnosis and treatment for ME can achieve excellent control. Eye salvage is possible in a select subset of patients by chemotherapy & plaque brachytherapy.

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