DR. ARUPJYOTI KAKATI

DR.JYOTI BHUYAN, DR.RITA DEKA

Abstract

Background: Type-2 Diabetes mellitus (T2DM) is chronic metabolic disease with multiple macro and microvascular complications. Diabetic macular oedema is a common manifestation of diabetic complications, the risk of which has been reported to be more with insulin use in recent literatures.

Methods: This cross-sectional study was carried out for a period of 6-months to explore the association between insulin use and diabetic macular edema as compared with oral hypoglycaemic agents (OHA). 40 T2DM patients who were taking either oral hypoglycemic agent (OHA) or insulin at least for 5 years were included in the study.

Results: In total 40 patients of T2DM 26 patients were taking OHA, while 14 were on Insulin. The frequency of diabetic macular edema was significantly higher in insulin group than OHA group (64.2% Vs 26.9%, P=0.0497).

Conclusion: Compared with OHA, insulin therapy may be associated with DR severity and Diabetic macular edema.