DR. TANWEESHA CHAKRABORTY

Dr.Sambuddha Ghosh

Abstract

Aim: Anxiety induces oxidative stress, and release of inflammatory markers which are risk factors for diabetic retinopathy (DR). High cortisol level worsens anxiety. We assessed association of diabetic retinopathy (DR) with anxiety.

 

Methods: Observational cross-sectional study with 112 middle-aged type 2 diabetes (T2DM) patients with LogMAR<0.48; 56 with DR and 56 without DR (NODR). Anxiety was measured by Hamilton Anxiety Rating scale (HAM-A). Cortisol was estimated by enzymatic method.   Results: Internal consistency was good (cronbach’s alpha = 0.723) . HAM-A in DR (14.4 ±6.5) was more (p=.001) than in NODR (10.4±4.1). Cortisol in DR (11.9±4.5mcg/dl) was more (p< .001) than in NODR (7.8±3.5mcg/dl). CRP in DR (7.4±7.2mg/L) was more(p<.001) than in NODR (3.6±3.7mg/L).   Conclusion: Anxiety is associated with DR in spite of good vision in middle-aged T2DM.

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