Dr.NISHTHA MISHRA

DR. KUMARI PRIYANKA VERMA, DR. ABHISHEK KUMAR SINHA, DR..RAJEEV KUMAR GUPTA

Abstract

Aim: to study etiology, clinical profile & treatment (t/t) outcome of PUK. Material & methods: 7 eye of 5 patients (pt.) with PUK were included. Demography, etiology, clinical features, t/t & outcome noted. Result:out of 5 pt., 3(59%) were male & 2 female. Mean age was 48.72 +/- 14.92 years. 80%of pt. were from rural area. 2 pt. had B/L involvement. 40% of pt. came after 4 weeks of symptoms. Of 7eyes, 2 had mild, 3 had moderate & 2 had severe disease. BCVA <3/60 was found in 2(28%) eye, mooren’s ulcer (MU) (40% eyes), RA factor was +ve in 1 pt. (20%). Of 5 pt., 4(80%) required systemic immunosuppression for the control of disease. Surgery required to maintain anatomical integrity in 2(28%) eyes. No significant change in vision was seen in pre & post t/t groups. Conclusion: PUK is an indicator of occult systemic autoimmune disease. MU is the most common cause of PUK. Prompt & adequate Immunosuppression is not only eye saving but also lifesaving for pt. with PUK of autoimmune origin.