Dr.ANIRBAN MANDAL

Dr.ASIM KUMAR GHOSH, Dr.PURBAN GANGULY

Abstract

ABSTRACT

Introduction: Thalassemia major patients have characteristic skeletal changes, including typical craniofacial changes.These changes in the patients might lead to an abnormal bony orbit and subsequently might lead to distinctive ocular biometry and/or refraction.

Materials and Methods: 523 Thalassemic children and 502 age and sex matched control population were selected by systematic random sampling. Comprehensive ophthalmological examination was done on both case and control groups.

Results and Analysis: The Thalassemic children had lower mean weight than the control group (p<0.03). The mean axial length of the eyeball was less (p=0.02) but the average lenticular thickness was comparatively more among Thalassemic Children (p<0.09). The average keratometry value was lower among the Thalassemic children (p=0.04) but astigmatism was more(p<0.02). Conclusion: Due to differential phenotypic expressions Thalassemic children may have abnormal ocular biometric characteristics.

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