DR DIVYA KUMARI

Dr. J. S. TITIYAL, Dr. NAMRATA SHARMA, DR. SRIDEVI NAIR

Abstract

Purpose: To compare outcomes of heparin-surface-modified (HSM) and non-HSM

hydrophobic acrylic intraocular lens (IOL) in diabetic patients undergoing

phacoemulsification.

Methods: Randomised controlled trial enrolled 100 eyes of 100 patients (HSM IOL=50; non

HSM IOL=50). Primary outcome measures were aqueous flare; central macular thickness

(CMT) and visual acuity (VA). Secondary outcome measures were IOL surface, posterior capsular opacity (PCO), and IOP.

outcome measures were assessed on POD1, 1 week, 1 month, 3 months, 6 months

and 1 year.

Results:significantly lower flare with HSM IOL on POD1 (9.9±5.2, 17.5±11.3, p=0.001),1

week (11.4±7.7, 17±9.4, p= 0.02) and 3 months (7.7±4.1, 12.5±5.6, p= 0.004). ACD was

longer in HSM IOL group on POD1 (p= 0.008), POD7 (p=0.001), 1 month (p<0.001) and 3 months (p=0.04). No significant difference in CME, IOP, PCO. Conclusion: Less inflammatory reaction with HSM IOL in early postoperative period that resolved faster in diabetics.

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